Backbone assignment of proteins with known structure using residual dipolar couplings
نویسندگان
چکیده
منابع مشابه
Backbone assignment of proteins with known structure using residual dipolar couplings.
A prerequisite for NMR studies of protein-ligand interactions or protein dynamics is the assignment of backbone resonances. Here we demonstrate that protein assignment can significantly be enhanced when experimental dipolar couplings (RDCs) are matched to values back-calculated from a known three-dimensional structure. In case of small proteins, the program MARS allows assignment of more than 9...
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ژورنال
عنوان ژورنال: Journal of Biomolecular NMR
سال: 2004
ISSN: 0925-2738
DOI: 10.1023/b:jnmr.0000042955.14647.77